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TitleWhite dot syndromes
PurposeThe aim of this presentation is to draw the attention to a heterogeneous group of rare autoimmune inflammatory diseases, where the clinical finding is dominated by an eruption, often typical for a given syndrome of the present multifocal microgranuloma in the choroidea, retinal pigment epithelium and the neuroretina.
MethodsThe syndromes are not attached to a systemic autoimmune disease. Most often they are an isolated bilateral eye disorder. This disorder can be divided in two groups with different prognosis. Monitoring of the disease activity is aided not only by the fundus photography in time, but also by autofluorescence, fluorescein and indocyanine angiography and OCT examinations. During differential diagnosis it is important to think about the granulomatous chorioretintis in the context of sarcoidosis, TBC, sympathetic ophthalmia, toxoplasmosis or the masking syndrome.
ResultsDuring treatment we administer corticosteroids perorally or by injection, we use immunosuppressants or biological therapy, or anti-VEGF treatment by injection into the eye in case a choroidal neovascularization develops.
ConclusionEven though WDS disease is rare, we should take it into account while working with the differential diagnosis of bilateral multifocal chorioretintis. In case of progressive syndromes early treatment can stabilize the disease.
Conflict of interestNo
Author 1
Last nameKARKANOVA
Initials of first name(s)M
DepartmentFaculty Hospital Ophthalmology and Medical Faculty at Masaryk University, Brno
CityBrno
CountryCzech Republic
Author 2
Last nameBeránek
Initials of first name(s)J
DepartmentFaculty Hospital Ophthalmology and Medical Faculty at Masaryk University, Brno
CityBrno
CountryCzech Republic
Author 3
Last nameVysloužilová
Initials of first name(s)D
DepartmentFaculty Hospital Ophthalmology and Medical Faculty at Masaryk University, Brno
CityBrno
CountryCzech Republic
Author 4
Last nameVlková
Initials of first name(s)E
DepartmentFaculty Hospital Ophthalmology and Medical Faculty at Masaryk University, Brno
CityBrno
CountryCzech Republic