Changing Uveitis Pattern in A Tertiary Institution in Northern of Thailand over 10 years
Purpose
This study aims to analyse the trends of uveitis patients visited at a referral center in Northern of Thailand in 2018.
Methods
We conducted a prospective analysis of 208 consecutive new cases of uveitis. Ophthalmologic examination and laboratory investigation were performed. Patient were classified by site, global uveitis causes, and etiology.
Results
A diagnosis of uveitis was established in 208 patients, including 119 male and 89 female patients with a mean age of 45-year-old. HIV associated uveitis was noted in 22.6% and most of them presented as posterior and panuveitis accounted for 87%. The most common uveitic etiology in this group was cytomegalovirus retinitis. In non-HIV group, anterior uveitis was the most frequent site (41%, 66/161). The infectious causes of this group were determined in 18% and toxoplasmosis is the most common identified organism (4.9%). And the most common non-infectious cause was VKH disease (6.2%). Interestingly, the incidence of syphilitic uveitis was increased during this period. The result shows 10 of 208 patients were infected by syphilis, compatible with raising in prevalence shown by national department of disease control.
Conclusion
HIV related uveitis was declined in incidence from 31% to 22.6% compared to previous report, conflicting to the rising in incidence of syphilitic uveitis. This finding may point out that sexual transmitted disease including HIV may not actual decrease as shown in the result, but CD4 count of the patients may maintained in the high value, due to improvement of HAART regimen.
Conflict of interest
No
Author 1
Last name
APIVATTHAKAKUL
Initials of first name(s)
A
Department
Ophthalmology
City
Chiangmai
Country
Thailand
Author 2
Last name
Pathanapitoon
Initials of first name(s)
K
Department
Ophthalmology
City
Chiangmai
Country
Thailand
Author 3
Last name
Kunavisarut
Initials of first name(s)
P
Department
Ophthalmology
City
Chiangmai
Country
Thailand
Author 4
Last name
Rothova
Initials of first name(s)
A
Department
Ophthalmology
City
Rotterdam
Country
Netherlands
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