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This abstract is assigned to session 18 - Free Papers III - Complications of Uveitis
Presentation preference Oral presentation
TitlePaediatric uveitic glaucoma and cataract in the time of biologic therapy
PurposeTo investigate rates, timing and visual outcomes of paediatric uveitic glaucoma and cataract in relation to the diagnosis and treatment of the uveitis with steroid sparing / biologic immunosuppression.
MethodsRetrospective chart review of all paediatric uveitis patients presenting to the Children’ s Hospital Westmead, Sydney Eye Hospital and Save Sight Institute from 2005- 2020.
Results111 patients (207 eyes) diagnosed with paediatric uveitis 2005-2020. The majority had bilateral uveitis (n = 89, 80%), 61 patients were female and 48 patients male, the most common aetiological diagnosis was JIA-U (n =65 , 59%), followed by idiopathic uveitis (n = 33, 29.6%) and anatomical diagnosis was 84% anterior uveitis and 16% non-anterior uveitis. Over 50% eyes diagnosed with uveitis developed raised IOP, close to 50% presumed to be steroid induced,
43 eyes (21%) had glaucoma surgery, 35 eyes had glaucoma drainage devices, 15 eyes had trabeculectomy surgery - the majority prior to 2017. Some eyes had two operations.
ConclusionControl of intraocular inflammation is essential. There should be a
rapid taper any systemic steroids, minimise topical steroid therapy to < 3 x per day (as OHT dose dependent), < 3 months duration, commence step ladder systemic more quickly ( IMT - MTX - Biologic)
Conflict of interestNo
Authors 1
Last nameZAGORA
Initials of first name(s)SL
DepartmentOphthalmology, Sydney Eye Hospital, University of Sydney and Westmead Children' Hospital
CitySydney
CountryAustralia
Authors 2
Last nameKaraconji
Initials of first name(s)TK
DepartmentOphthalmology, Sydney Eye Hospital, University of Sydney and Westmead Children' Hospital
CitySydney
CountryAustralia
Authors 3
Last nameMcCluskey
Initials of first name(s)PJ
DepartmentOphthalmology, Sydney Eye Hospital, University of Sydney
CitySydney
CountryAustralia
Authors 4
Last nameGrigg
Initials of first name(s)J
DepartmentOphthalmology, Sydney Eye Hospital, University of Sydney and Westmead Children' Hospital
CitySydney
CountryAustralia