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TitleThe use of electrophysiology to augment multimodal imaging in inflammatory choroidopathies
PurposeTo further highlight where electrodiagnosis augments our multimodal imaging in a spectrum of White Dot Syndromes.
MethodsA retrospective case series of patients seen at the Uveitis unit at Sydney Eye Hospital and Electrophysiology department at Save Sight Institute between 2005-2019. Data pertaining to clinical history, examination, multimodal imaging, electrophysiology findings and treatment modalities was collected.
Results115 patients (190 eyes) were included. Diagnoses included Multifocal Choroiditis with Panuveitis (MFCPU) (31.3%), Acute Zonal Occult Outer Retinopathy (AZOOR) (29.6%), Birdshot Chorioretinopathy (BCR) (14.8%), Punctate Inner Choroidopathy (PIC) (12.2%) and Multiple Evanescent White Dot Syndrome (MEWDS) (4.3%). The average age was 40.9 years. The majority of patients were female (67%), Caucasian (77.4%) and had bilateral ocular involvement (65.2%). Mean visual acuity was 20/60 at initial review and 20/40 at final review. MCFPU, AZOOR, BCR and PIC accounted for 93.8% of 65 WDS patients that underwent electrophysiology. Electrophysiology helped confirm the final diagnosis in 97.1% of AZOOR and 88.2% of BCR (p=.000073).
ConclusionThis study highlights how clinical findings and multimodal imaging are sufficient to diagnose MFCPU and PIC. Electrophysiology is needed to diagnose, monitor treatment response and inform the visual prognosis in patients with AZOOR and BCR.
Conflict of interestNo
Authors 1
Last nameLIM
Initials of first name(s)B
DepartmentSave Sight Institute - University of Sydney (SSI - USYD), Sydney Eye Hospital (SEH)
CitySydney
CountryAustralia
Authors 2
Last nameZagora
Initials of first name(s)S
DepartmentSSI - USYD, SEH
CitySydney
CountryAustralia
Authors 3
Last nameCornish
Initials of first name(s)E
DepartmentSSI - USYD, SEH
CitySydney
CountryAustralia
Authors 4
Last nameGrigg
Initials of first name(s)J
DepartmentSSI - USYD, SEH
CitySydney
CountryAustralia
Authors 5
Last nameMcCluskey
Initials of first name(s)P
DepartmentSSI - USYD, SEH
CitySydney
CountryAustralia