Nl-Fr

View abstract

This abstract is assigned to session 18 - Free Papers III - Complications of Uveitis
Presentation preference Oral presentation
TitleOcular complications in children with idiopathic chronic anterior uveitis
PurposeTo describe the course and development of ocular complications in children with idiopathic chronic anterior uveitis (CAU).
MethodsData of 48 patients (83 affected eyes) with idiopathic CAU were collected retrospectively. Outcome measures were: visual acuity, systemic treatment, ocular complications and surgery. Outcomes of children with a younger (≤8 years) and older onset of uveitis (>8 years) were compared using Cox proportional hazard analysis with correction for paired eyes.
ResultsMedian age of onset of uveitis was 7.8 years (range 3.3-16). Bilateral disease was present in 35 patients (73%). Fifteen patients (31%) were treated with systemic corticosteroids. Thirty-six patients (75%) were treated with immunomodulatory therapy, of whom 29% (n=14) were treated with an additional biological agent. Complications were present in 43% of the affected eyes at onset of uveitis and increased to 74% at 5 years of follow-up. At 5 years of follow-up the younger age group suffered more frequently from posterior synechiae (HR 2.6, p<0.01) and secondary glaucoma (HR 16, p=0.02), and needed more cataract surgery (HR 4.8, p<0.01). Visual acuity was significantly worse in the younger age group (0.15 vs 0.00 logMAR, p<0.001), but improved at 5 years of follow-up (0.05 vs 0.00 logMAR, p=0.82).
ConclusionVision-threatening ocular complications occur in the majority of the children with idiopathic CAU. They are more common in children with a younger age of onset of uveitis and are frequently being present at onset. Nevertheless, long-term vision usually stays good.
Conflict of interestNo
Authors 1
Last nameKOUWENBERG
Initials of first name(s)CV
DepartmentOphthalmology
CityUtrecht
CountryNetherlands
Authors 2
Last nameShahabi
Initials of first name(s)M
DepartmentOphthalmology
CityUtrecht
CountryNetherlands
Authors 3
Last namede Boer
Initials of first name(s)JH
DepartmentOphthalmology
CityUtrecht
CountryNetherlands
Authors 4
Last nameKoopman-Kalinina Ayuso
Initials of first name(s)V
DepartmentOphthalmology
CityUtrecht
CountryNetherlands