| Presentation preference | Oral presentation |
| Title | Role of screening for uveitis in subjects with sarcoidosis |
| Purpose | Ocular involvement is common in sarcoidosis. Our study aimed to evaluate the role of screening for uveitis in subjects with sarcoidosis. |
| Methods | Retrospective case series of 88 subjects with a pre-existing diagnosis of sarcoidosis, with no previous diagnosis of uveitis, reviewed by Ophthalmology at Auckland District Health Board between January 2016 and May 2022. |
| Results | Sarcoid uveitis was diagnosed in 50 subjects (56.8%), and 45 required ocular treatment. In those presenting with acute eye symptoms, uveitis was observed in 94.1% (32 out of 34 subjects) while in those undergoing a screening examination, uveitis was observed in 27.8% (15 out of 54 subjects). Sarcoid uveitis was observed in 6 out of 27 subjects (22.2%) who were entirely asymptomatic at screening. On multivariate analysis, blurring of vision (OR 26.2 p<0.001), eye pain (OR 7.3 p=0.014) and respiratory disease (OR 7.1 p=0.044) were associated with increased risk of sarcoid uveitis. In the 41 subjects with no uveitis at initial examination, 3 subjects (7.3%) subsequently developed uveitis. |
| Conclusion | Our study highlights the importance of ophthalmic screening of all patients with systemic sarcoidosis, even in asymptomatic patients. With a high correlation of ocular symptoms in diagnosis of sarcoid uveitis, ophthalmologists should educate patients to look out for the development of symptoms of ocular inflammation, and clinicians who continue follow up for systemic sarcoidosis should remind patients to watch carefully for these symptoms to facilitate timely diagnosis and intervention. |
| Conflict of interest | No |
Authors 1
| Last name | KOH |
| Initials of first name(s) | LHL |
| Department | Ophthalmology |
| City | Singapore |
| Country | Singapore |
Authors 2
| Last name | Sims |
| Initials of first name(s) | JL |
| Department | Ophthalmology |
| City | Auckland |
| Country | New Zealand |
Authors 3
| Last name | Pepin |
| Initials of first name(s) | F |
| Department | Ophthalmology |
| City | Quebec |
| Country | Canada |
Authors 4
| Last name | Wilsher |
| Initials of first name(s) | M |
| Department | Respiratory Services |
| City | Auckland |
| Country | New Zealand |
Authors 5
| Last name | Niederer |
| Initials of first name(s) | RL |
| Department | Ophthalmology |
| City | Auckland |
| Country | New Zealand |
