| Presentation preference | Oral presentation |
| Title | Outcomes of early vitrectomy with 25-gauge or 27-gauge microincision vitrectomy system for acute retinal necrosis |
| Purpose | To investigate the treatment outcomes of early vitrectomy with microincision vitrectomy system (MIVS) for acute retinal necrosis (ARN). |
| Methods | This retrospective study included 10 patients (11 eyes) who were diagnosed with ARN and underwent 25-gauge or 27-gauge vitrectomy before the onset of retinal detachment at Kobe University Hospital between April 2017 and October 2021. Patients were followed up for at least 6 months after surgery. |
| Results | Of the 10 eyes analyzed by vitreous fluid PCR, 6 had varicella-zoster virus and 4 had herpes simplex virus. The mean age of the 6 female and 4 male patients was 59.4 years. The progression of necrotic lesions was observed in Zone 1 in 3 eyes, Zone 2 in 6 eyes, and Zone 3 in 2 eyes. In the initial surgery, 27-gauge vitrectomy was chosen for 7 eyes (63.6%), silicon oil (SO) was injected in 10 eyes (91%), and encircling scleral buckling was combined in 7 eyes (64%). Intraoperative complications included corneal epithelial edema in 2 eyes and iatrogenic retinal breaks in 1 eye. During a mean follow-up period of 25 months, SO was successfully removed in 9 eyes, retinal detachment occurred in 3 eyes, and retinal reattachment was not achieved in 1 eye. The logMAR visual acuity 6 months after surgery was 0.00 or better (decimal visual acuity of 1.0 or higher) in 5 eyes (46%). The mean logMAR visual acuity significantly improved from 0.90±1.00 before surgery to 0.57±1.00 6 months after surgery (P=0.03). |
| Conclusion | Early vitrectomy with MIVS for ARN can achieve safe and favorable treatment outcomes. |
| Conflict of interest | No |
Authors 1
| Last name | MATSUMIYA |
| Initials of first name(s) | W |
| Department | Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine |
| City | Kobe |
| Country | Japan |
Authors 2
| Last name | Kusuhara |
| Initials of first name(s) | S |
| Department | Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine |
| City | Kobe |
| Country | Japan |
Authors 3
| Last name | Sotani |
| Initials of first name(s) | R |
| Department | Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine |
| City | Kobe |
| Country | Japan |
Authors 4
| Last name | Sotani |
| Initials of first name(s) | Y |
| Department | Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine |
| City | Kobe |
| Country | Japan |
Authors 5
| Last name | Sakai |
| Initials of first name(s) | D |
| Department | Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine |
| City | Kobe |
| Country | Japan |
Authors 6
| Last name | Yamada |
| Initials of first name(s) | H |
| Department | Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine |
| City | Kobe |
| Country | Japan |
Authors 7
| Last name | Imai |
| Initials of first name(s) | H |
| Department | Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine |
| City | Kobe |
| Country | Japan |
Authors 8
| Last name | Nakamura |
| Initials of first name(s) | M |
| Department | Division of Ophthalmology, Department of Surgery, Kobe University Graduate School of Medicine |
| City | Kobe |
| Country | Japan |
