| Presentation preference | Poster presentation |
| Title | From the eye to the gut |
| Purpose | Extraintestinal manifestations (EIM) of Inflammatory Bowel Disease may be the first clinical evidence of disease. Our purpose is to describe the case of a new-onset optic nevritis associated with a previously undiagnosed Ulcerative Colitis (UC). |
| Methods | Case-report |
| Results | A 20-year-old male patient presented to the Ophthalmology Department complaining of diminished vision. He had an ocular history of a recurrent alternating nongranulomatous anterior uveitis, which was under etiological investigation. His past medical history was relevant for a left paramedian pontine acute ischemic stroke, without an established etiology despite intensive evaluation and diagnostic testing. Family history was positive for Crohn and Celiac disease. His visual acuity was 0.6 (decimal scale) in both eyes. Biomicroscopy revealed recurrence of anterior uveitis in RE. Fundoscopy revealed left optic disc swelling with macular edema. Fluorescein angiography showed bilateral optic disc edema, more accentuated in LE, with peripapillary dye leakage. Optical coherence tomography revealed bilateral optic disc edema with secondary subfoveal detachment in LE and standard automated perimetry revealed a left blind spot enlargement. Although no other systemic symptoms or signs were found, further examination showed increased fecal calprotectin level and the patient underwent upper gastrointestinal endoscopy and colonoscopy, whose anatomopathological findings were highly suggestive of UC. 5-aminosalicylic acid therapy successfully improved both ophthalmological and gastrointestinal findings. |
| Conclusion | Although rare, optic nevritis is a potentially severe EIM of UC which may occur in otherwise asymptomatic young patients. A multidisciplinary cooperation is necessary for the management of these patients. |
| Conflict of interest | No |
Authors 1
| Last name | PINTO PROENÇA |
| Initials of first name(s) | R |
| Department | Ophthalmology, Centro Hospitalar e Universitário de Lisboa Central |
| City | Lisboa |
| Country | Portugal |
Authors 2
| Last name | MOTA |
| Initials of first name(s) | C |
| Department | Ophthalmology, Centro Hospitalar e Universitário de Lisboa Central |
| City | Lisboa |
| Country | Portugal |
Authors 3
| Last name | Cunha |
| Initials of first name(s) | B |
| Department | Ophthalmology, Centro Hospitalar e Universitário de Lisboa Central |
| City | Lisboa |
| Country | Portugal |
Authors 4
| Last name | Ludovico |
| Initials of first name(s) | I |
| Department | Ophthalmology, Centro Hospitalar e Universitário de Lisboa Central |
| City | Lisboa |
| Country | Portugal |
Authors 5
| Last name | Alves |
| Initials of first name(s) | N |
| Department | Ophthalmology, Centro Hospitalar e Universitário de Lisboa Central |
| City | Lisboa |
| Country | Portugal |
Authors 6
| Last name | Jorge |
| Initials of first name(s) | I |
| Department | Ophthalmology, Hospital de Cascais, Dr. José de Almeida |
| City | Lisboa |
| Country | Portugal |
Authors 7
| Last name | Guedes |
| Initials of first name(s) | M |
| Department | Ophthalmology, Centro Hospitalar de Lisboa Ocidental |
| City | Lisboa |
| Country | Portugal |
Authors 8
| Last name | LOPES |
| Initials of first name(s) | E |
| Department | Ophthalmology, Centro Hospitalar e Universitário de Lisboa Central |
| City | Lisboa |
| Country | Portugal |
Authors 9
| Last name | Pires |
| Initials of first name(s) | G |
| Department | Ophthalmology, Centro Hospitalar e Universitário de Lisboa Central |
| City | Lisboa |
| Country | Portugal |
