| Presentation preference | Poster presentation |
| Title | Non-infectious uveitis treated with 0,19 mg fluocinolone acetonide intravitreal implant (ILUVIEN®): a real-world case series |
| Purpose | Assess the effectiveness and safety profile of 0,19 mg fluocinolone acetonide intravitreal implant (FAc; ILUVIEN®) in patients with uveitis in the clinical practice. |
| Methods | Retrospective case-series analysis of 8 eyes (4 patients) with non-infectious uveitis. |
| Results | This analysis included: 6 eyes with idiopathic panuveitis and 2 with rheumatoid arthritis-associated uveitis, with a mean±standard deviation follow-up time post-FAc of 16±8 months. At baseline 75% presented macular edema, 75% posterior synechia, 25% glaucoma and 63% were phakic (1 eye with cataract). In 38% eyes the last treatment prior FAc implant was dexamethasone implant. At baseline, 63% were under topical treatment and 50% under systemic therapy. Median visual acuity was 62±24 letters, central retinal thickness (CRT) was 367±116 µm and intraocular pressure (IOP) was 13±3 mmHg. Regarding intraocular inflammation (IOI): 25% and 50% of eyes had a A/C cells and VH, respectively. Post-FAc implantation the visual acuity improved +15 letters (p< 0.05), anatomically eyes reached a median of 303±56 µm (p> 0.05), and in terms of IOI, 88% and 100% eyes achieved an A/C cells and VH grade 0, respectively. None needed supplemental intravitreal therapy post-FAc and, versus baseline, 80% and 50% of eyes had a topical and systemic therapy -sparing effect, respectively. thirteen percent of eyes were treated with emergent IOP-lowering medications and 3 eyes (60%) underwent cataract surgery |
| Conclusion | In this case series FAc showed benefit in the control of active intraocular inflammation: with most of eyes having visual acuity gain, improvement of macular edema, topical and systemic therapy sparing effect. |
| Conflict of interest | No |
Authors 1
| Last name | BESELGA |
| Initials of first name(s) | D |
| Department | Ophtalmology Department - Centro Hospitalar Barreiro Montijo, Portugal |
| City | Barreiro |
| Country | Portugal |
Authors 2
| Last name | Martins |
| Initials of first name(s) | L |
| Department | Ophtalmology Department - Centro Hospitalar Barreiro Montijo, Portugal |
| City | Barreiro |
| Country | Portugal |
Authors 3
| Last name | Ribeiro |
| Initials of first name(s) | MJ |
| Department | Ophtalmology Department - Centro Hospitalar Barreiro Montijo, Portugal |
| City | Barreiro |
| Country | Portugal |
Authors 4
| Last name | Borges |
| Initials of first name(s) | B |
| Department | Ophtalmology Department - Centro Hospitalar Barreiro Montijo, Portugal |
| City | Barreiro |
| Country | Portugal |
Authors 5
| Last name | Pedrosa |
| Initials of first name(s) | C |
| Department | Ophtalmology Department - Centro Hospitalar Barreiro Montijo, Portugal |
| City | Barreiro |
| Country | Portugal |
Authors 6
| Last name | Marreiros |
| Initials of first name(s) | M |
| Department | Ophtalmology Department - Centro Hospitalar Barreiro Montijo, Portugal |
| City | Barreiro |
| Country | Portugal |
Authors 7
| Last name | Francisco |
| Initials of first name(s) | D |
| Department | Ophtalmology Department - Centro Hospitalar Barreiro Montijo, Portugal |
| City | Barreiro |
| Country | Portugal |
Authors 8
| Last name | Portela |
| Initials of first name(s) | D |
| Department | Ophtalmology Department - Centro Hospitalar Barreiro Montijo, Portugal |
| City | Barreiro |
| Country | Portugal |
