| Presentation preference | Poster presentation |
| Title | Clinical Profile of Various Types of Serpiginous Choroiditis In a Tertiary eye center in South India |
| Accept poster if oral is not possible ? | Yes |
| Purpose | To study the visual outcome and profile of serpiginous choroiditis (SC) in a tertiary eye center in South India |
| Methods | A retrospective cohort study was conducted on 61 patients diagnosed with serpiginous choroiditis between 2018 and 2023. Patients were classified into three groups: Group 1 (lesions around the optic disc spreading centrifugally), Group 2 (macular SC), and Group 3 (multifocal serpiginoid choroiditis). Ophthalmic and systemic investigations were performed on blood and ocular fluids. |
| Results | The study analyzed 95 eyes from 61 patients, grouped into Group 1 (optic disc lesions spreading centrifugally), Group 2 (macular serpiginous choroiditis), and Group 3 (peripheral origin with features of Groups 1 and 2). The average age was 33.26 ± 11.56 years, with a male-to-female ratio of 43:18. Significant visual acuity improvement post-treatment was observed in Group 1 (p=0.044) and Group 2 (p=0.011), while Group 3 maintained due to lesser severity (p=0.465). Optical Coherence Tomography showed external limiting membrane disruption in all groups.
Mycophenolate mofetil was the most common drug (42.62%), followed by azathioprine (31.15%) and antiviral drugs (4.92%). Oral steroids with immunosuppressives were used in severe cases. Selected cases received posterior sub-tenon, intravitreal dexamethasone, or anti-VEGF injections for cystoid macular edema and choroidal neovascular membrane. Tuberculosis prevalence significantly increased (63.93%; p<0.0001) and was identified as the cause in 39 patients.
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| Conclusion | The profile of serpiginous choroiditis forms a shifting paradigm in terms of etiology and management. |
| Conflict of interest | No |
1
| Last name | MATHEW |
| Initials of first name(s) | N R |
| Department | Department of Uvea and Medical retina |
| City | Chennai |
| Country | India |
2
| Last name | Janakiraman |
| Initials of first name(s) | P |
| Department | Department of Uvea |
| City | Chennai |
| Country | India |
3
| Last name | Biswas |
| Initials of first name(s) | J |
| Department | Director of Uveitis & Ocular Pathology Department, |
| City | Chennai |
| Country | India |
