| Presentation preference | Poster presentation |
| Title | Diagnosis of Herpetic Anterior Uveitis Using Aqueous Humor PCR in Patients with a Previous History of Dengue Fever |
| Accept poster if oral is not possible ? | Yes |
| Purpose | Dengue is a viral infection affects millions of people, particularly in tropical and subtropical regions. Ocular manifestations like uveitis are rare. However, an emerging theory suggests that dengue may act as a trigger for the reactivation of latent viruses within the body, including Herpes Virus. Additionally, physical and emotional stressors, such as surgical procedures, can also lead to viral reactivation.
The use of polymerase chain reaction (PCR), has proven essential for the accurate diagnosis of these conditions. The confirmation of viral DNA in aqueous humor via PCR is a crucial diagnostic tool, particularly in cases where clinical manifestations may be confused with other etiologies.
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| Methods | Case Report |
| Results | Case 1: a 28-year-old woman, presented with unilateral hypertensive non-granulomatous anterior uveitis, with intraocular pressure (IOP) measured at 50 mmHg. She had a history of dengue with positive serological one week prior to the onset of ocular symptoms. PCR testing of the aqueous humor confirmed the presence of HSV-1.
Case 2: a 32-year-old woman, presented with granulomatous anterior uveitis, characterized by normal IOP and areas of sectoral iris atrophy. Her medical history revealed a recent dengue infection and a cesarean delivery three months prior. PCR testing of the aqueous humor confirmed the presence of HSV-1.
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| Conclusion | Both cases underscore the importance of considering recent viral infections, such as dengue, and significant stress events, like surgery, as potential triggers for the reactivation of latent viruses such as HSV-1. The integration of molecular diagnostics, particularly PCR, is pivotal in accurately diagnosing and managing these cases. |
| Conflict of interest | No |
1
| Last name | ZANETTI PATRICIO DE MACEDO |
| Initials of first name(s) | B |
| Department | Clínica Moacir Cunha/ Grupo Fleury |
| City | São Paulo |
| Country | Brazil |
2
| Last name | Cunha |
| Initials of first name(s) | L |
| Department | Clínica Moacir Cunha/ Grupo Fleury |
| City | São Paulo |
| Country | Brazil |
3
| Last name | Andrade |
| Initials of first name(s) | G |
| Department | Clínica Moacir Cunha/ Grupo Fleury |
| City | São Paulo |
| Country | Brazil |
4
| Last name | Granato |
| Initials of first name(s) | C |
| Department | Clínica Moacir Cunha/ Grupo Fleury |
| City | São Paulo |
| Country | Brazil |
5
| Last name | Lazary |
| Initials of first name(s) | C |
| Department | Clínica Moacir Cunha/ Grupo Fleury |
| City | São Paulo |
| Country | Brazil |
6
| Last name | Samico |
| Initials of first name(s) | G |
| Department | Clínica Moacir Cunha/ Grupo Fleury |
| City | São Paulo |
| Country | Brazil |
7
| Last name | Trahtman Boer |
| Initials of first name(s) | D |
| Department | Clínica Moacir Cunha/ Grupo Fleury |
| City | São Paulo |
| Country | Brazil |
8
| Last name | Finamor |
| Initials of first name(s) | L |
| Department | Clínica Moacir Cunha/ Grupo Fleury |
| City | São Paulo |
| Country | Brazil |
