Retinal and choroidal inflammations in eyeball specimens supported by molecular pathological study
Purpose
To study the pattern of choroidal and retinal inflammations in pathological eyeballs with immuno-histochemical staining in a tertiary institute of northeast India.
Methods
Design- laboratory based study.
Enucleated eyeballs and eviscerated eyes where studied in the ophthalmic pathology laboratory .Gross, histopathological analysis and immunohistochemistry were done in the cases and documented.Retinal and choroidal tissues were studied for the inflammation. Clinical diagnosis were noted from case files. Retinal and choroidal vessels' caliber were analyzed particularly for the thickness of the walls of the blood vessels which were inflamed from normal blood vessels. Basic statistical tools were used to compare them.
Results
Total (n= 13) cases were studied of which (n= 8) cases were sympathetic ophthalmia (SO). Diffuse stromal choroditis were seen in 6 cases of SO. In 4 cases, endophthalmitis were evident with retinal layer inflammation. In one case (n=1) inflammatory epiretinal membrane was documented.
Conclusion
Retinal and choroidal inflammations secondary to inflammatory and infectious process were important to know the pattern of involvement.
Conflict of interest
No
Author 1
Last name
DAS
Initials of first name(s)
D
Department
Uveitis, Ocular Pathology & Neuro-Ophthalmology Services, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 2
Last name
Bhattacharjee
Initials of first name(s)
H
Department
Vitreo-Retina, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 3
Last name
Upadhaya
Initials of first name(s)
A
Department
Vitroretina
City
GUWAHATI
Country
India
Author 4
Last name
Bhattacharjee
Initials of first name(s)
K
Department
Orbit & Oculoplasty, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 5
Last name
Soibam
Initials of first name(s)
R
Department
Vitroretina, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 6
Last name
Kuri
Initials of first name(s)
GK
Department
Orbit & Oculoplasty, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 7
Last name
Deka
Initials of first name(s)
P
Department
Ocular Pathology, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
Author 8
Last name
Deka
Initials of first name(s)
A
Department
Ocular Pathology, Sri Sankaradeva Nethralaya
City
GUWAHATI
Country
India
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