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Presentation preference Poster and Rapid fire
review resultPoster and Rapid fire
TitleToxoplasmosis in Sydney Australia - a Retrospective cohort
Accept poster if oral is not possible ?Yes
Purposeto determine the seveity and clinical course of ocular toxoplasmosis in a major Australian referral center
MethodsRetrospective review of patient files who presented to Sydney Eye Hospital between 2007 and 2017 with clinical features consistent with ocular toxoplasmosis. Visual acuity and relapse rate compared to other studies in ocular toxoplasmosis
Results48 patients with ocular toxoplasmosis who presented to Sydney Eye Hospital during the period of observation. The median age was 35.5 (IQR 21-50) with 29 (60%) having no previous symptomatic episodes or evidence of chorioretinal scarring. Visual acuity at presentation was 0.51 or 6/19 (SE 0.096) and at follow up 0.31 or 6/9 (SE 0.094). 9 patients experienced a recurrence during the period of observation with time to recurrence 2.2 years (SE 0.45). The relapse rate (1 or more) 0.09/person-year. Location of lesion was predominantly within the vascular arcades (n=44) with macular involvement in 9 patients. Most patients received clindamycin therapy (n=34).
ConclusionPatients with ocular toxoplasmosis had fewer recurrences compared with other published series and had better visual recovery. The majority of patients received clindamycin and oral prednisolone which was well tolerated with pyrimethazine and sulfadiazine reserved for those with macula involving disease.
Conflict of interestNo
Author 1
Last nameYATES
Initials of first name(s)W
DepartmentSave Sight Institute, The University of Sydney
CitySydney
CountryAustralia
Author 2
Last nameZagora
Initials of first name(s)S
DepartmentSave Sight Institute, The University of Sydney
CitySydney
CountryAustralia
Author 3
Last nameMcCluskey
Initials of first name(s)P
DepartmentSave Sight Institute, The University of Sydney
CitySydney
CountryAustralia
Author 4
Last nameChoong
Initials of first name(s)F
DepartmentDepartment of Infectious Diseases, Prince of Wales
CitySydney
CountryAustralia
Author 5
Last namePost
Initials of first name(s)J
DepartmentDepartment of Infectious Diseases, Prince of Wales
CitySydney
CountryAustralia
Author 6
Last nameWakefield
Initials of first name(s)D
DepartmentSchool of Medical Sciences, Sydney Australia
CitySydney
CountryAustralia