Characterization of Glaucoma in Vogt-Koyanagi-Harada Disease
Purpose
To know the prevalence and mechanisms of glaucoma in the eyes of patients with Vogt-Koyanagi-Harada disease (VKH).
Methods
Material and Methods: Retrospective observational study of a series of 326 eyes of 164 patients diagnosed with VKH from the Institute of Ophthalmology "Fundación Conde de Valenciana" seen during the 2001-2018 period. The eyes were classified into two groups according to the presence of glaucoma and clinical and demographic information was obtained.
Results
Results: A glaucoma prevalence of 20.6% was found. The majority of the population with VKH were women (73.8%) with an average age of 39.04 (± 12.98) years and with 41.12 (± 47.97) months of follow-up. In the glaucoma group, the most frequent presentation stage was chronic-recurrent (64.2%), the angle was closed in (82.1%) and the most frequent complications were the anterior synechiae (86.6%), posterior synechiae (76.1%), iris bombé (25%) and cataract (53.7%). The eyes without glaucoma developed ocular hypertension in 26.1% of the cases. The final visual acuity was better in the eyes without glaucoma (0.45 ± 0.63) compared with the eyes with glaucoma (1.70 ± 105). The control of the intraocular pressure was obtained in 64.2% through the use of 1-3 hypotensive drugs in 71.6% of the cases. The most frequent surgery was the Ahmed valve implant in 34.4% followed by the 14.9% iridectomy.
Conclusion
The prevalence of glaucoma was similar to that reported in the literature. The secondary angular closure disease is higher that reported with diverse mechanisms unique to VKH disease.
Conflict of interest
No
Author 1
Last name
ALVAREZ
Initials of first name(s)
C
Department
Tecnologico de Monterrey
City
Monterrey
Country
Mexico
Author 2
Last name
RODRIGUEZ-GARCIA
Initials of first name(s)
A
Department
Tecnologico de Monterrey
City
MONTERREY
Country
Mexico
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