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This abstract is assigned to session Free Paper Session IV: Infectious Disease II
Presentation preference Oral
review resultOral
TitleRetinal Vasculitis and Posterior Pole Hypopyon in Exogenous Bacterial Endophthalmitis
Accept poster if oral is not possible ?Yes
PurposeTo investigate the clinical settings and visual outcomes in eyes with exogenous bacterial endophthalmitis with retinal vasculitis and posterior pole hypopyon.
MethodsRetrospective, consecutive, interventional case series.
Results The clinical settings included cataract extraction (n = 30), trauma (n = 5), trabeculectomy with bleb (n = 2), penetrating keratoplasty (n = 1), pars plana vitrectomy (PPV) (n = 1), and iridoplasty (n = 1). Presenting visual acuity (VA) ranged from hand motions to no light perception. Patients were treated with PPV with the infusion of antibiotics (10 μg/mL vancomycin and either 40 μg/mL ceftazidime or 10 μg/mL amikacin) and dexamethasone (10 μg/mL), removal of vitreous and posterior pole hypopyon, and intravitreal injections of antibiotics and dexamethasone at the end of surgery. The risk factors for poor visual outcomes were initial poor VA (P < .001), older age (P = .021), virulent organism (P < .001), diffuse retinal vasculitis (P = .009), diffuse posterior pole hypopyon (P < .001), ocular hypertension (P < .001), retinal detachment (P = .005), and silicone oil tamponade (P = .004). Multivariate linear regression revealed that diffuse posterior pole hypopyon (P = .005) and ocular hypertension (P = .012) were the significant independent factors for poor visual outcomes.
ConclusionDiffuse posterior pole hypopyon and ocular hypertension are critical prognostic factors for poor visual outcomes. Most cases of retinal vasculitis and focal posterior pole hypopyon can resolve without sequelae, and favorable visual outcomes can be achieved in these cases.
Conflict of interestNo
Author 1
Last nameCHEN
Initials of first name(s)KJ
DepartmentOphthalmology
CityTaoyuan
CountryTaiwan
Author 2
Last nameCHEN
Initials of first name(s)YP
DepartmentOphthalmology
CityTaoyuan
CountryTaiwan