| Presentation preference | Poster presentation |
| Title | Long-term outcomes and risk factors for prognosis in elective and non-elective vitrectomies for uveitis patients |
| Purpose | To evaluate the long-term outcomes of pars plana vitrectomy(PPV) in uveitis patients and assess the effect of the surgical indication (elective or non-elective PPV) on these outcomes. |
| Methods | This is a retrospective review of the records of all patients who attended a uveitis clinic at Moorfields Eye Hospital, UK between 2011 to 2019. The patients included, had chronic uveitis treated with topical or systemic therapy and PPV and had a minimum 5 year-follow-up post PPV. |
| Results | Overall, 77 patients were included and classified in non-elective (nE-PPV) group (35 patients) and elective PPV (E-PPV) group (33 patients). The significant differences between the 2 groups were the PPV indications (nE-PPV: retinal detachment (84.6%); E-PPV: epiretinal membrane (45.2%)), the time from the last flare-up to PPV (nE-PPV: 3.3 ± 4.6 months; E-PPV: 9.0 ± 8.2 months) and the BCVA gain more than 2 lines at 1 year post PPV (nE-PPV: 33.3%; E-PPV: 66.7%). The postoperative relapses in the 2 groups were associated with the age, the presence of panuveitis and long duration of disease. The factors contributing to post-PPV BCVA indicated that after adjusting for time and surgical type, E-PPV compared to nE-PPV was estimated to improve logMAR BCVA by -0.30(P=0.037); poor baseline BCVA was associated with BCVA decrease by 0.63(P<0.001); and improvement of BCVA at 1 year follow-up compared to baseline was associated with -0.17 estimate better of BCVA(P=0.008). |
| Conclusion | Our study showed that whether urgent or elective PPV in treating uveitis could be beneficial for the post-PPV visual outcomes. Importantly, the first postoperative year BCVA could play a detrimental factor for the long-term visual outcomes. |
| Conflict of interest | No |
Authors 1
| Last name | TASIOPOULOU |
| Initials of first name(s) | A |
| Department | Eye Center of Athens, Moorfields Eye Hospital |
| City | Athens |
| Country | Greece |
Authors 2
| Last name | Chen |
| Initials of first name(s) | YH |
| Department | Ophthalmology, Chang Gung Memorial Hospital, Linkou medical center, Moorfields Eye Hospital |
| City | Taoyuan |
| Country | Taiwan |
Authors 3
| Last name | Lavnish |
| Initials of first name(s) | J |
| Department | UCL Institute of Ophthalmology, Moorfields Eye Hospital |
| City | London |
| Country | United Kingdom |
Authors 4
| Last name | Lightman |
| Initials of first name(s) | S |
| Department | UCL Institute of Ophthalmology, Moorfields Eye Hospital |
| City | London |
| Country | United Kingdom |
Authors 5
| Last name | Tomkins-Netzer |
| Initials of first name(s) | O |
| Department | UCL Institute of Ophthalmology, Moorfields Eye Hospital, Lady Davis Carmel Medical Center |
| City | Haifa |
| Country | Israel |
