| Presentation preference | Poster presentation |
| Title | Focal yellow lesion at macula: the mimickers of Toxoplasma retinitis |
| Accept poster if oral is not possible ? | Yes |
| Purpose | To demonstrate various atypical presentations of retinitis at macula mimicking Toxoplasma retinochoroiditis (TRC). |
| Methods | Retrospective case series wherein the lesions mimicked and were diagnosed as TRC at the presenting visit. |
| Results | 14 patients were recruited of whom eight received antiparasitic therapy which was later changed to etiology specific treatment. The commonest mimicker we noted in this series was focal fungal retinitis (seven eyes, microbiologically proven in six eyes) followed by Tubercular focal chorioretinitis (four eyes), Toxocara retinitis (two eyes) and Syphilitic (one eye). Most common feature that led to the diagnostic bias initially was focal retinitis adjacent to pigmented scar (n=8) followed by vitritis (n=5 ) and vasculitis (n=1). Revision of diagnosis was based on clues from OCT combined with with deep vitreous biopsy (seven cases). Fundus evaluation and fundus photo based clues included – 1. whitish coloured retinitis 2. Subretinal nodular/abscess-like lesion 3.Choroidal granuloma with subretinal fibrous exudation. OCT features leading to revision of diagnosis from Toxoplasma retinitis were 1. Subretinal location of lesion with or without rain cloud sign 2. Choroidal granuloma with subretinal fibrin mimicking as Toxoplasma retinitis lesion. 3. Compact intraretinal infiltrate 4. Absence of choroidal thickening |
| Conclusion | Focal yellow lesion with an adjacent pigmented scar; mimicking Toxoplasma retinitis was seen due to fungal retinitis, Tubercular chorioretinitis, Toxocara and/or syphilis as the mimickers. They could be differentiated based on a combination of clinical features, multimodal imaging, deep vitreous biopsy and/or serological diagnoses. |
| Conflict of interest | No |
1
| Last name | KELGAONKAR |
| Initials of first name(s) | Anup |
| Department | Uveitis, vitreous and retina |
| City | Bhubaneswar |
| Country | India |
2
| Last name | Jadhav |
| Initials of first name(s) | V |
| Department | Uveitis, vitreous and retina |
| City | Visakhapatnam |
| Country | India |
