This abstract is assigned to sessions
| Presentation preference | Poster presentation |
| Title | The impact between Optic Neuritis and Inflammatory Bowel Disease |
| Purpose | To investigate the possible factors associated with optic neuritis (ON) in patients with inflammatory bowel disease (IBD). |
| Methods | we analyzed the Taiwan National Health Insurance Research Database (NHIRD) from the years 2000 to 2013. Patients with IBD were on the index date. All the patients were followed up until the development of ON or the end of the study period. |
| Results | The mean follow-up time was 7.13 ± 5.21 years. At the study period, eight and five patients with and without IBD, respectively, had developed ON (p = 0.001). Adjusted HRs showed that patients with IBD aged between 30 and 39 years, with comorbidities including neuromyelitis optica (NMO), acute disseminated encephalomyelitis (ADEM), systemic lupus erythematosus (SLE) and with a higher Charlson Comorbidity Index, had a significantly higher risk of developing ON (all p < 0.005). Among the eight IBD patients who developed ON, only one patient was diagnosed with Crohn's disease, the male gender was slightly dominant, and two patients received anti-tumor necrosis factor α treatment for IBD. Patients with IBD have a higher risk of developing ON compared to patients without IBD. ON occurs more frequently in IBD patients aged between 30 and 39 years, with comorbidities including NMO, ADEM and SLE. |
| Conclusion | Patients with IBD have a higher risk of developing ON. Thus, examination of visual acuity in patients with IBD is important, especially patients with a higher risk of ON. |
| Conflict of interest | No |
Authors 1
| Last name | CHEN |
| Initials of first name(s) | C-L |
| Department | Department of ophthalmology, Tri-Service General Hospital, National Defence Medical Center |
| City | Taipei |
| Country | Taiwan |
Authors 2
| Last name | Hsieh |
| Initials of first name(s) | Y-H |
| Department | Department of ophthalmology, Tri-Service General Hospital, National Defence Medical Center |
| City | Taipei |
| Country | Taiwan |
