This abstract is assigned to sessions
| Presentation preference | Poster presentation |
| Title | Multiple evanescent white dot syndrome following BNT162b2 mRNA COVID-19 vaccination. |
| Purpose | To report a case with multiple evanescent white dot syndrome (MEWDS) following COVID-19 vaccination. |
| Methods | Case presentation |
| Results | Case : A 67-year-old female presented with central visual field loss in the right eye (OD) for 5 days since one day after second dose of BNT162b2 mRNA COVID-19 vaccine. At the initial visit, best corrected visual acuity (BCVA) in decimal points was 0.2 OD and 1.0 in the left eye (OS). Ophthalmic examination showed multifocal white dots in the posterior retina OD. Multimodal imaging OD showed diffuse disruption of ellipsoid zone on OCT, punctate hyperfluorescence in a wreath-like pattern and late staining on fluorescein angiography, and multiple hypofluorescent spots in the late phases on indocyanine green angiography. One week later, there were disappearing multifocal white dots OD. No active intraocular inflammation or abnormality had been seen in the left eye. One more week later, her BCVA OD was spontaneously improved to 0.8 without any treatment. Collectively, these clinical findings led to the diagnosis of MEWDS after mRNA COVID-19 vaccination. |
| Conclusion | COVID-19 vaccination could induce MEWDS with vision loss. |
| Conflict of interest | No |
Authors 1
| Last name | MATSUMIYA |
| Initials of first name(s) | W |
| Department | Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine |
| City | Kobe |
| Country | Japan |
Authors 2
| Last name | YASUDA |
| Initials of first name(s) | E |
| Department | Department of Ophthalmology, Kakogawa Central City Hospital |
| City | Kakogawa |
| Country | Japan |
Authors 3
| Last name | MAEDA |
| Initials of first name(s) | Y |
| Department | Department of Ophthalmology, Kakogawa Central City Hospital |
| City | Kakogawa |
| Country | Japan |
Authors 4
| Last name | KUSUHARA |
| Initials of first name(s) | S |
| Department | Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine |
| City | Kobe |
| Country | Japan |
Authors 5
| Last name | NAKAMURA |
| Initials of first name(s) | M |
| Department | Department of Surgery, Division of Ophthalmology, Kobe University Graduate School of Medicine |
| City | Kobe |
| Country | Japan |
Authors 6
| Last name | HARA |
| Initials of first name(s) | R |
| Department | Department of Ophthalmology, Kakogawa Central City Hospital |
| City | Kakogawa |
| Country | Japan |
