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This abstract is assigned to session Free Paper Session I: Diagnosis and Monitoring
Presentation preference Oral
review resultOral
TitleVertical hyperreflective lesions. An OCT finding in vitreoretinal lymphoma.
Accept poster if oral is not possible ?Yes
PurposeTo describe an imaging finding seen on optical coherence tomography (OCT) of patients with vitreoretinal lymphoma (VRL).
MethodsWe retrospectively reviewed charts of patients diagnosed with vitreoretinal lymphoma at the Department of Ophthalmology, Northwestern University, Chicago, between 2014 and 2018. Color fundus photography and fundus autofluorescence images, as well as OCT scans of the patient were collected and analyzed.
ResultsWe identified 7 patients (12 eyes) with intraocular lymphoma involving the retina (5 patients with primary vitreoretinal or central nervous system lymphoma (CNSL) with ocular involvement, one patient with testicular lymphoma with secondary CNSL and VRL, and one patient with systemic lymphoma and secondary vitreoretinal lymphoma). We identified vertical hyperreflective lesions (VHRL) that showed moderate or high reflectivity and affected all layers of the neuroretina in 5 patients (7 out of 12 eyes). These often preceded the development of sub-retinal pigment epithelial (subRPE) deposits and were often localized around 2nd and 3rd order retinal vessels. In most cases, they resolved with minimal or no scarring after initiation of chemotherapy.
ConclusionWe describe vertical hyperreflective lesion which is a common physical finding on OCT in eyes with vitreoretinal lymphoma.
Conflict of interestNo
Author 1
Last nameDEáK
Initials of first name(s)GG
DepartmentDepartment of Ophthalmology, Medical University of Vienna
CityVienna
CountryAustria
Author 2
Last nameJampol
Initials of first name(s)LM
DepartmentDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University
CityChicago
CountryUnited States
Author 3
Last nameGoldstein
Initials of first name(s)DA
DepartmentDepartment of Ophthalmology, Feinberg School of Medicine, Northwestern University
CityChicago
CountryUnited States