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TitleIRVAN syndrome: A retrospective review of 9 cases from Tunisia
PurposeTo describe clinical features, relevant imaging findings, disease course, and response to treatment in 9 patients (18 eyes) with IRVAN syndrome.
MethodsA retrospective study about nine patients (18 eyes) diagnosed with IRVAN syndrome
ResultsMean age was 33.5 years (4 males and 5 females). Mean initial best-corrected visual acuity (BCVA) was 20/32. Clinical findings included peripapillary exudates in 11 eyes, partial or complete macular star in 11 eyes, multiple aneurysmal dilatations of the retinal and/or optic nerve-head arterioles in 8 eyes, and vascular sheathing in 11 eyes. Thirteen eyes had the stage 2 of the disease, 3 eyes had the stage 3 and 2 eyes had the stage 1. Treatment modalities included peripheral scatter photocoagulation (14 eyes), intravitreal bevacizumab (4 eyes), and intravitreal triamcinolone acetonide (1 eye). Final BCVA was less than or equal to 20/200 in 5 eyes.
ConclusionIRVAN is a rare idiopathic ocular condition. Prognosis may be guarded despite treatment.
Conflict of interestNo
Authors 1
Last nameZINA
Initials of first name(s)S
DepartmentDepartment of Ophthalmology, Fattouma Bourguiba University Hospital, University of Monastir, Tunisia
CityMonastir
CountryTunisia
Authors 2
Last nameFEKIH
Initials of first name(s)K
DepartmentDepartment of Ophthalmology, Fattouma Bourguiba University Hospital, University of Monastir, Tunisia
CityMonastir
CountryTunisia
Authors 3
Last nameNAMSIA
Initials of first name(s)W
DepartmentDepartment of Ophthalmology, Fattouma Bourguiba University Hospital, University of Monastir, Tunisia
CityMonastir
CountryTunisia
Authors 4
Last nameHADJ AMOR
Initials of first name(s)W
DepartmentDepartment of Ophthalmology, Fattouma Bourguiba University Hospital, University of Monastir, Tunisia
CityMonastir
CountryTunisia
Authors 5
Last nameABROUG
Initials of first name(s)N
DepartmentDepartment of Ophthalmology, Fattouma Bourguiba University Hospital, University of Monastir, Tunisia
CityMonastir
CountryTunisia
Authors 6
Last nameKHAIRALLAH
Initials of first name(s)M
DepartmentDepartment of Ophthalmology, Fattouma Bourguiba University Hospital, University of Monastir, Tunisia
CityMonastir
CountryTunisia