Long-Term Clinical Outcomes of Patients with Sympathetic Ophthalmia
Purpose
To present the long-term clinical outcomes of patients with sympathetic ophthalmia (SO).
Methods
Retrospective review of patients’ medical files between 2002 and the present time.
Results
Included were seven patients (four males). The mean ±SD age at presentation was 38± 23.5 years. Four patients had co-morbidities: three were diabetic (+/- HTN and hyperlipidemia), and one had Turner Syndrome. Trauma was the inciting event in six patients and postoperative endophthalmitis in one patient. Decreased visual acuity (VA) was the leading symptom in the sympathizing eye, and all patients presented with panuveitis clinically.
The mean ±SD interval between the incident and the onset of SO in six cases was 4.3± 4.2 months. One case presented 30 years after the eye injury.
Inflammation was partially controlled in two patients. Four cases underwent enucleation and one case evisceration. The presenting mean ±SD BCVA in the sympathizing eye was 0.49±0.29, and the final mean ±SD BCVA was 0.52 ±0.37. The mean follow-up time was 6.4 years.
Conclusion
SO is one of the most sight-threatening conditions, affecting the healthy eye. Visual prognosis is directly related to prompt diagnosis and treatment. In this cohort, the favorable visual outcome was mainly seen in young and healthy individuals.
Conflict of interest
No
Authors 1
Last name
MAVRIS
Initials of first name(s)
N
Department
Department of Ophthalmology, Hadassah Medical Center
City
Jerusalem
Country
Israel
Authors 2
Last name
AMER
Initials of first name(s)
R
Department
Department of Ophthalmology, Hadassah Medical Center
City
Jerusalem
Country
Israel
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