Massive uveal effusion induced by topical Latanoprost in a nanophthalmic patient
Purpose
To report a case of massive uveal effusion after treatment with topical latanoprost in a nanophtalmic patient.
Methods
case report.
Results
A 61-year-old male patient, was referred for bilateral vision loss. At presentation, best-corrected-visual-acuity was 20/200 with a refraction of +18 dioptres in the right eye and 20/400 with a refraction of +20 dioptres in the left eye. Intraocular pressure was 14-mmgh OU. Fundus examination revealed a crowded optic disc with an elevated retinal papillomacular (PM) fold OU. Macular-OCT showed retinal PM folds with cystoid cavities in the inner retinal layers, and shallow serous-retinal-detachment (SRD) involving the macula OU. B-scan ultrasonography showed bilateral foreshortening of the eye with a sclerochoroidal thickening. The diagnosis of uveal effusion syndrome (UES) complicating nanophthalmia was made. A drainage sclerotomy was scheduled but delayed because of general anaesthetic problem. Topical corticosteroids and latanoprost were prescribed. Ten days later, the patient presented with loss of vision limited to light perception OU. Funduscopy showed a huge bilateral retrolental bullous SRD. Latanoprost was discontinued. Full-thickness-sclerotomy was performed in the both eyes with gradual anatomical and functionnal improvement.
Conclusion
UES is a known complication in nanophtalmic eyes. Prostaglandins analogs are thought to increase fluid or protein movement across the sclera and has been used as therapeutic option in this condition. Paradoxically, the use of these agents has been associated with uveal effusions in patients with Sturge-Weber syndome. To the best of our knowledge, this is the first reported case of exacerbation of uveal effusion in nanophtalmic eyes.
Conflict of interest
No
Authors 1
Last name
MAHJOUB
Initials of first name(s)
A
Department
Department of ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
City
MONASTIR
Country
Tunisia
Authors 2
Last name
ABROUG
Initials of first name(s)
N
Department
Department of ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
City
MONASTIR
Country
Tunisia
Authors 3
Last name
TRIMECHE
Initials of first name(s)
I
Department
Department of ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
City
MONASTIR
Country
Tunisia
Authors 4
Last name
BEN SAIDI
Initials of first name(s)
O
Department
Department of ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
City
MONASTIR
Country
Tunisia
Authors 5
Last name
JELLITI
Initials of first name(s)
B
Department
Department of ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
City
MONASTIR
Country
Tunisia
Authors 6
Last name
KHAIRALLAH
Initials of first name(s)
M
Department
Department of ophthalmology, Fattouma Bourguiba University Hospital, Monastir, Tunisia
City
MONASTIR
Country
Tunisia
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