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TitleUnilateral Cytomegalovirus Retinitis in a Patient with Systemic Lupus Erythematosus
PurposeThe purpose of this study is to report a rare case of cytomegalovirus (CMV) retinitis in a seronegative patient with systemic lupus erythematosus (SLE) on immunosuppressive therapy.
MethodsA seronegative 55-year-old female patient with SLE who was on immunosuppressive therapy developed CMV retinitis. The immunosuppressive therapy was tapered, and the patient was given intravitreal ganciclovir in addition to systemic ganciclovir. The follow-up visits were documented.
ResultsThe patient responded to the treatment and gradual resolution of lesion was observed.
ConclusionCMV retinitis is a progressive devastating retinal condition. Patients on immunosuppressive therapy should be referred to an ophthalmologist for periodic check-up for early diagnosis and treatment of this devastating ophthalmic condition. For clinically progrssive CMV retinitis in seronegative patients with SLE, a combination therapy of intravitreal and intravenous ganciclovir is useful.
Conflict of interestNo
Authors 1
Last nameCHANG
Initials of first name(s)YC
DepartmentDepartment of Ophthalmology, Kaohsiung Municipal Ta-Tung Hospital
CityKaohsiung
CountryTaiwan
Authors 2
Last nameChen
Initials of first name(s)KJ
DepartmentDepartment of Ophthalmology, Kaohsiung Municipal Siaogang Hospital
CityKaohsiung
CountryTaiwan
Authors 3
Last nameSheu
Initials of first name(s)SJ
DepartmentDepartment of Ophthalmology, Kaohsiung Medical University Hospital
CityKaohsiung
CountryTaiwan