View abstract

This abstract is assigned to sessions
Presentation preference Poster presentation
TitleBacillary Layer Detachment in Acute Vogt-Koyanagi-Harada disease
PurposeThis study aims to report the frequency and the impact of bacillary layer detachment (BLD) on clinical outcomes in patients with acute Vogt-Koyanagi-Harada (VKH) syndrome.
MethodsPatients with initial-onset acute VKH syndrome were retrospectively reviewed. The characteristics of optical coherence tomography (OCT) were recorded and their association with clinical outcomes were analyzed.
ResultsAll patients received systemic high-dose corticosteroid pulse therapy except for one pediatric case, who received combined intravenous corticosteroid mini-pulse therapy and oral cyclosporine. The time to complete resolution of subretinal fluid was 40.03 ± 27.087 days and the time to recovery of best corrected visual acuity (BCVA) was 75.64 ± 84.454 days. No significant differences were found between eyes with BLD and without BLD regarding the time to resolution of subretinal fluid (36.67 ± 14.171 vs 29.82 ± 13.884, p=0.214) and the time to recovery of BCVA (67.89 ± 62.552 vs 75.18 ± 124.173, p=0.835). Similarly, there was no significant difference between eyes with fovea-splitting BLD and fovea-sparing BLD regarding the time to recovery of BCVA (73.33 ± 74.313 vs 67.13 ± 103.100, p=0.861).
ConclusionBLD is a common OCT characteristic in acute VKH. The presence of BLD does not seem to prolong the time interval of visual recovery. This result is compatible with current evidence that certain plasticity of photoreceptor layer exists to allow rapid functional recovery despite a split in the inner segment layer.
Conflict of interestNo
Authors 1
Last nameHWANG
Initials of first name(s)DK
DepartmentTaipei Veterans General Hospital
Authors 2
Last nameHung
Initials of first name(s)WC
DepartmentTaipei Veterans General Hospital